ClCKB is a key determinant of tubular reabsorption of chloride and electrolytes along the distal tubule. A severe salt-losing tubulopathy (Bartter syndrome type III) develops if ClCKB is ...

Tubular glucose reabsorption is performed by the combined ... Modest rises in hematocrit and blood urea nitrogen (24 weeks plus 24 weeks extension) DP(5/10 mg) plus pioglitazone ≥30 mg/day ...