Co-expression of helper and cytotoxic ... for provision of T-cell help for the generation of self-MHC restricted T-cell responses to tumor peptides. The optimal allogeneic dendritic cell for ...

Furthermore, the group led by Feldman at the Weizmann Institute had studied changes in MHC expression associated with tumor metastasis in mice. In some cases, metastatic cells had lost MHC ...

"These two enzymes control the proper expression levels of MHC-II molecule. In a tumor, if you lose BAP1, you lose that balance. In this case, in BAP1 depleted tumor cells, you can rebalance the ...

The first patient has been dosed in the phase 3 TACTI-004 trial evaluating efti with Keytruda and chemotherapy for advanced ...

Helin Norberg and Dr. Erik Norberg, have identified a previously unknown mechanism that affects the ability of cancer cells to spread in the body. The study, published in EMBO Molecular Medicine ...

Shanghai Juncell Therapeutics Co., Ltd. (Juncell Therapeutics), a clinical-stage biotech developing innovative IL-2-independent Tumor-Infiltrating Lymphocyte (TIL) therapies for cancers, announced ...