The cancer microenvironment, or tumour microenvironment, describes the non-cancerous cells present in the tumour. These include fibroblasts, immune cells and cells that comprise the blood vessels.

A recent study uncovers how drug-resistant cancer cells induce changes in the tumor microenvironment. This phenomenon ...

for cancer therapy is limited by the hypoxia in the tumor microenvironment and the antioxidant defense. Here, the authors address these limitations by developing a tumor microenvironment ...

An immuno-oncology targeting panel accurately characterized tumor-resident immune cells and located pathologically and clinically relevant tumor microenvironment features. Cancer development and ...

Russell W. Jenkins, MD, PhD, a physician investigator in the Krantz Family Center for Cancer Research at the Mass General Cancer Center and an ...

HIF1α identified as key regulator that induces cancer-killing ability of hypoxic T cells, playing a role in ICB resistance.

In a new paper, published in Nature Cancer, first author Tharp and colleagues illuminate how the fibrotic tumor microenvironment creates an inhospitable milieu for anti-tumor immunity. Kelly ...

Drug resistance poses a significant challenge to the success of cancer treatments. A new study reveals the mechanisms behind its development and ...

Image Credit: CI Photos / Shutterstock.com In a recent study published in Nature ... examine the interplay between cancer cells and monocytes in the tumor microenvironment, explore how oncogenic ...

We are focusing on the regulation of growth and phenotype in embryonic and metastatic stem cells, mesenchymal cells and immune cells in the tumor microenvironment. The work incorporates signal ... and ...