The short arm was soon identified, by Margaret Dayhoff, as ubiquitin, a 76-residue protein of unknown function that was described (as a free protein) by Gideon Goldstein and colleagues in 1975 (ref.

Intrinsically disordered proteins (IDPs) are subject to ubiquitin-independent degradation, a default and passive process. We describe here a model wherein a group of 'nanny' proteins function to ...

Ubiquitin ligases regulate many processes in ... Dimerization is, therefore, an important regulatory mechanism." "If HACE1 no longer functions correctly in the cell or is missing altogether ...

Scientists have uncovered the intricate circuit cues behind neuronal cell maturation and migration, which is required for proper cognitive function.