They identified all known E1s and a previously uncharacterized protein, UBA6 (also known as UBE1L2 (ubiquitin-activating enzyme E1-like 2)). UBA6 also contains a CCD and a UFD so, by domain ...

The first concerns the verb defining ubiquitin transfer to a protein: is it (1) to ubiquitinylate or (2) to ubiquitylate or (3) to ubiquitinate? It does not matter which, I would just like to see ...

E1 enzymes facilitate conjugation of ubiquitin and ubiquitin-like proteins through adenylation ... SUMO-PCNA signals for recruitment of the anti-recombinogenic helicase Srs2 and we were able to ...

Ubiquitin ligases regulate many processes in living cells. Depending on how many ubiquitin molecules they attach to the target proteins and in which way, they control the protein's fate. "The ...