The quest for VEGF and other factors that promote tumour angiogenesis was initiated many decades ago, and a long and complicated path has led to the development of inhibitors of these molecules as ...

These findings raise the question of whether retroviral VEGF gene therapy is useful for therapeutic ‘angiogenesis’ without risking ‘angioma-genesis’. Overexpression of VEGF may lead to an ...

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The ranibizumab biosimilar Ongavia exhibited significantly less improvement in visual acuity and retinal thickness compared ...

Human extracellular matrices can be edited in their composition using the CRISPR/Cas9 system, leading to materials exhibiting tailored regenerative capacities.

Summit Therapeutics' ivonescimab shows strong efficacy in trials, with Cantor Fitzgerald predicting a 50% market share in the ...

Lu says the new study demonstrates that, instead of inhibiting dysfunctional tumor angiogenesis by anti-VEGF agents, inducing healthy vasculature by dCNP could reinvigorate anti-tumor immunity and ...

The BM microenvironment encompasses a wide spectrum of cell types and extracellular matrix proteins, including fibronectin, collagen, laminin and osteopontin. Multistep genetic and ...

Several studies have also shown that vascular endothelial growth factor (VEGF) can increase the efficiency of skeletal muscle repair by increasing angiogenesis and, at the same time, reducing the ...