Venetoclax combined with Roche’s Gazyva (obinutuzumab) is already in phase 1 development in previously untreated CLL, and in phase 2 as a monotherapy in first line CLL with a 17p13 deletion.
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plus venetoclax and obinutuzumab; the combination resulted in undetectable minimal residual disease in 81% of patients at one year. Pirtobrutinib was also the subject of the BRUIN CLL-321 trial ...
"Patients with treatment-naive CLL have several treatment options, including continuous BTK inhibitor therapy, fixed-duration venetoclax-based regimens, and chemoimmunotherapy, for low-risk ...
Here are the 5 most-viewed CLL/SLL pieces of 2024. 5. Real-World Study Confirms Efficacy of Venetoclax Alone, After BTKi Therapy in CLL According to this summary of findings shared at the 2023 ...
Suggested remit: To appraise the clinical and cost effectiveness of acalabrutinib and venetoclax with or without obinutuzumab within its marketing authorisation for previously untreated chronic ...