These deficits progress to severe paraparesis. Disinhibition and hyperactivity have been reported at 2 to 3 months of age. Homozygous mice develop deficits in hippocampal-dependent visuospatial memory ...

and visuospatial abilities. Physical performance tests measured grip strength, balance, walking speed, leg muscle strength, and functional mobility with a “sit to stand” task (how long does it ...