Glycolysis is a central metabolic pathway by which cells obtain energy from sugar. Cancer cells in particular have long been thought to depend on the energy obtained through glycolysis, a phenomenon ...

This makes the results published by Almut Schulze and colleagues from the German Cancer Research Center (DKFZ) all the more surprising: when the researchers blocked the enzyme aldolase A, which ...

Scientists at the German Cancer Research Center (DKFZ) have now shown that liver cancer cells in mice and humans depend on a key enzyme of glycolysis, Aldolase A. When it is switched off ...