强友们，现在微信改版了，阅读之前先“关注”+“星标”吧~每天第一时间看到最新强直科普文章强直性脊柱炎（AS），这个名字听起来像个冷冰冰的医学术语，但它背后却隐藏着一段关于“基因”和“细菌”的复杂纠葛。许多人都听过“HLA-B27”，这个被誉为强直性脊 ...

强直性脊柱炎（AS）被称为 “不死的癌症”，而 HLA-B27 阳性者更被贴上 “高危标签”。数据显示，90% 的 AS 患者携带 HLA-B27 基因，但仅有 5-10% 的阳性者会发病 —— 这一矛盾揭示了单纯基因检测无法解释疾病全貌。传统西医治疗以非甾体抗炎药（NSAIDs）、生物制剂（如 TNF-α 抑制剂）为主，但部分患者面临耐药性、感染风险或经济负担。 李征的突破点：他发现 ...

HLA-B27 positivity is linked to higher odds of non-remission in patients with juvenile idiopathic arthritis at 18 years after ...

强直性脊柱炎，这一令众多患者痛苦不堪的慢性疾病，如同隐匿在身体内部的 ...

研究发现，HLA-B27基因在该病的发生中起着重要作用，而这个基因可以通过遗传传播。 那么，作为一名“强直妈妈”，你需要注意哪些问题？如何在 ...

Researchers have found in a new research that HLA-B27 genetic marker is linked to a higher risk of various arthropathies, ...

The exact cause of the juvenile ankylosing spondylitis is unknown. The disease is strongly linked to a gene known as HLA-B27. Approximately 80-90% of children with JAS have the HLA-B27 gene.

3.hla-b27抗原化验：如果怀疑是强直性脊柱炎引起的疼痛不适症状，则需要进行hla-b27抗原化验，明确是否存在此类病变。 通常情况下，HLA-B27抗原化验 ...

More than 8 out of 10 people, or 80%, with ankylosing spondylitis carry the HLA-B27 gene. The prevalence of this gene varies in different ethnic populations. This compares with around 6% to 8% of ...

Determining the specificity of HLA antibodies is arguably one of the most important contributions by the HLA laboratory today. For patients that have low-to-moderate levels of antibody ...