Coronary plaque rupture is known to be a major cause of sudden coronary death, but it is also commonly seen in non-coronary sudden death, and can be a clinically silent cause of plaque progression.

It is known to be associated with circulating LDL and is highly upregulated in macrophages undergoing apoptosis in the necrotic plaque core. It can also contribute to the generation of the key ...

The condition is “high-risk” plaque, once narrowly defined as plaque built up in the arteries that is likely to rupture, possibly leading to an acute heart attack or sudden cardiac death.

With “plaque rupture” or “plaque erosion,” the thin fibrous cap covering the plaque is disrupted or ulcerated. This exposes the blood flow to tissue factor, activates the clotting cascade ...

February was heart month, and this is the last column in a series about the major risk factors for heart attacks. Heart attacks are not all about cholesterol—inflammation plays a large role. There are ...

Despite advances in its understanding and treatment, coronary heart disease remains the leading cause of death worldwide. Acute coronary syndromes most commonly result as a consequence of the rupture ...