Researchers are conducting a groundbreaking trial that could revolutionize the way the body fights cancer, particularly for ...

First, like Ras, Rho family proteins serve as guanine ... activate kinase cascades, regulate gene expression, regulate membrane trafficking, promote growth transformation and induce apoptosis.

it has become clear that KRAS-mutant cancers can quickly evolve to resist therapies targeted at one specific form of the gene ...

Adding immunotherapy to a new type of inhibitor that targets multiple forms of the cancer-causing gene mutation KRAS kept ... In this study, the researchers used RAS(ON) multi-selective inhibitors ...