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CYP2D6 基因多态性如何影响乳腺癌患者他莫昔芬副作用?研究揭示关键 ...
乳腺癌是全球重大健康问题,他莫昔芬(Tamoxifen)常用于雌激素受体阳性(ER + )乳腺癌治疗,但 CYP2D6 基因多态性影响其代谢和副作用。研究人员对 86 例患者研究发现,CYP2D6 活性降低与子宫毒性增加有关,为临床用药监测提供依据。
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