Calcium pyrophosphate deposition disease (CPPD) is a form of arthritis characterized by the accumulation of calcium pyrophosphate crystals in the joints, leading to inflammation and pain.

“We demonstrated that both Il1r1 −/− mice and mice pre-treated with mIL-1 Trap showed reduced neutrophil influx in MSU and calcium pyrophosphate dihydrate crystal-induced peritonitis and air ...