Enhancers are regions of DNA that act as molecular switches for turning genes on or off. Understanding enhancer function is very important, since they contain the majority of genetic variants ...

Enhancers are regions of DNA that act as molecular switches for turning genes on or off. Understanding enhancer function is very important, since they contain the majority of genetic variants ...

Neuropsychiatric disorders are becoming increasingly prevalent. Given their complex and multifactorial pathogenesis, there is ...

Enhancers were formerly believed to be modular. Each enhancer occupies a separate region of DNA, as the term suggests. “We have shown, however, that this is not absolutely true," explained ...

After TFs bind to promoter or enhancer regions of the DNA, they interact with other bound TFs and recruit RNA polymerase II. Their influence, however, can be either positive or negative ...