The chromatin landscape is a key aspect of epigenetic regulation in eukaryotes ... of heritable transcription regulation from two model systems, yeast and Drosophila melanogaster, in which ...

In recent years, biomedical laboratory research has undergone tremendous change, to the extent that computers have frequently replaced test tubes. In this context, many discoveries now start with ...

To do so, they developed a transgenic mouse model carrying a slime mold endonuclease that ... the team observed that DNA breaks and subsequent repair lead to the erosion of the epigenetic landscape.

Chromosomal rearrangements, such as chromosome segment inversions, may affect the epigenetic landscape as well as ... inversions of different sizes in the model plant Arabidopsis thaliana.