Background and aims The transcription factor sex-determining region Y-related high-mobility group-box gene 9 (SOX9) plays a critical role in organ development. Although SOX9 has been implicated in ...

Previous research has shown that mammals accumulate LCA during calorie restriction and it activates a key molecule involved in metabolism called AMP-activated protein kinase, or AMPK. AMPK ...

Why AMPK Is Crucial AMPK (adenosine monophosphate-activated protein kinase) is often dubbed the “metabolic master switch”: Inhibits Excess Fat Storage: AMPK works to block carbs from turning ...