研究结论和讨论部分指出，IVDD 由多种因素引发，当前治疗手段无法阻止其进展。本研究首次证实 Piezo1 参与 IVDD，它通过增加软骨细胞 ROS 生成、提高氧化应激水平、促进 ECM 降解、引发炎症反应和诱导细胞凋亡等方式，推动椎间盘退变。Yap 在 Piezo1 下游发挥作用，介导其信号转导。抑制 Yap 可改善 CEP 退变。这一研究为 IVDD ...

为探究福氏耐格里阿米巴（Naegleria fowleri）致病机制，研究人员聚焦 nf-profilin 与 nf-actin，发现二者表达模式互补，对理解其致病性意义重大。 福氏耐格里阿米巴（Naegleria fowleri），这个名字听起来或许有些陌生，但它却隐藏着巨大的威胁。它是一种自由生活的 ...

A discovery by Mayo Clinic researchers may help explain why immunotherapy hasn't been helpful for many patients with ...

Published in Clinical Cancer Research, their study identifies specific proteins, fibronectin and smooth muscle actin, in ...

The actin filament exists as a structure of the fixed length and bears the muscle contraction and the adjustment on a muscular inside. The circulation and the molecule movements of the polymerization ...

A discovery by Mayo Clinic researchers may help explain why immunotherapy hasn't been helpful for many patients with metastatic colorectal cancer. In findings published in Clinical Cancer Research, ...

The new study, published in the journal Nature Communications, reveals that actin—a protein in butterfly's ...

The actin cytoskeleton provides force for dynamic cellular processes, such as motility, morphogenesis, cell division, endocytosis, and phagocytosis. The organization and dynamics of actin filaments ...

Are you unsure whether Cipla Actin is actually the best option for your weight-gain requirements? It's a worthwhile question ...