Patients are prone to airway contraction when cells lose cyclic adenosine monophosphate. Patients with asthma had higher average serum cAMP levels than patients who did not have asthma.

Solid lines represent direct actions, while dashed lines indicate indirect or secondary effects. β1-AR, Beta-1 Adrenergic Receptor; AC, Adenylyl Cyclase; cAMP, Cyclic Adenosine Monophosphate; PDE, ...

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The paper, which will appear in the Journal of Clinical Investigation, found that patients with asthma have dramatically elevated levels of a molecule called cyclic adenosine monophosphate (cAMP) in ...

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