Eplerenone, a specific aldosterone receptor blocker with a lower incidence of the sex hormone-related side effects than spironolactone, has been used in several recent clinical trials in ...

depends on the type, but may lead to ankle swelling, flushing, constipation, slow heart rate, or heart palpitations Aldosterone receptor antagonists These are used mainly in cases of heart failure ...

The effects of angiotensin include vasoconstriction and stimulation of aldosterone production. Inhibiting angiotensin receptors will decrease blood pressure through vasodilation and blockade of ...

Dropsy, described in the 17th century, treated with “cure de dechloruration” (bloodletting, leeching, and lancing) and a ...

investigated whether adding the aldosterone receptor antagonist spironolactone to renin–angiotensin system inhibition improved proteinuria in patients with diabetic nephropathy. Patients with ...

The trial aims to determine the effects of aldosterone receptor antagonism on mortality and cardiovascular outcomes (onset or progression of cardiovascular disease) in patients with stage 3b CKD ...

Disclosure: The author has been the recipient of research grant support from Pharmacia for participation in some of the research studies described herein and presented data from these studies at ...