New York, NY) is an aldosterone blocker that works by binding at the mineralocorticoid receptor. It has some similarities to the potassium-sparing diuretic spironolactone, but rarely causes ...

Recent studies have highlighted the challenges of managing potassium levels in patients with CKD, particularly those receiving renin-angiotensin-aldosterone system inhibitors (RAASi), which are ...

When Marsha McCarty-Coombs was diagnosed with Conn's Syndrome at the age of 39, doctors told her to "get her papers in order" ...

The primary naturally occurring mineralocorticoid is aldosterone – it’s primary ... (such as hypertension and CHF) and loss of potassium. Anaphylactoid reactions have been reported very ...

Aldosterone antagonists (spironolactone and epleronone) have additional antihypertensive effects, especially at doses used for HF. They are indicated for patients with stage C and stage D HF.

Heart failure is a condition that occurs when the heart can’t pump as well as it should. This may happen when the heart muscle becomes weak or stiff. As a result, it doesn’t deliver enough blood to ...