Dysregulation of IC molecules has been described in several autoimmune diseases; however, little is known about the role of ICs in anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis ...

5 A new EUVAS (European Vasculitis Study Group) study has demonstrated that capture ELISA is superior to direct ELISA for PR3-ANCA detection in Wegener's granulomatosis. 6 The best strategy to ...

Objective To compare two long-term remission maintenance strategies for antineutrophil cytoplasmic antibody (ANCA) vasculitis. Methods We conducted a prospective, single-centre, open-label, randomised ...

Avacopan is under clinical development by Amgen and currently in Phase III for Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis (ANCA Vasculitis). According to GlobalData, Phase III drugs ...

Objectives The RITUXVAS trial reported similar remission induction rates and safety between rituximab and cyclophosphamide based regimens for antineutrophil cytoplasm antibody (ANCA)-associated ...

Despite this, serum MPO ANCA titres were not suppressed and had been detectable from the age of 16 ... As well as possible infective and malignant causes, vasculitis must also be considered as a rare, ...

MT-2990 is under clinical development by Mitsubishi Tanabe Pharma and currently in Phase I for Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis (ANCA Vasculitis). According to GlobalData, ...

A 79-year-old keen cyclist from Willunga man credits positive thinking with saving him from a rare disease, ANCA vasculitis, after he experienced severe pains while in Thailand. Roger Fabray ...

Objectives A few studies on antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) treatments have shown the therapeutic efficacy of mycophenolate mofetil (MMF). However, the ...

1 Department of Rheumatology and Immunology, Peking University International Hospital, Beijing, China 2 Department of Pathology, Peking University International Hospital, Beijing, China ...

We learned that abatacept did not reduce the risk of relapse in ANCA-associated vasculitis. There was a lot of efforts in the past years of looking and investigating EGPA, eosinophilic ...