Online supplemental table 1 shows the baseline characteristics of the validation cohort ... Although PD-1 axis dysregulation has been observed in different autoimmune disorders, little is known about ...

5 A new EUVAS (European Vasculitis Study Group) study has demonstrated that capture ELISA is superior to direct ELISA for PR3-ANCA detection in Wegener's granulomatosis. 6 The best strategy to ...

Objective To compare two long-term remission maintenance strategies for antineutrophil cytoplasmic antibody (ANCA) vasculitis. Methods We conducted a prospective, single-centre, open-label, randomised ...

Objectives The RITUXVAS trial reported similar remission induction rates and safety between rituximab and cyclophosphamide based regimens for antineutrophil cytoplasm antibody (ANCA)-associated ...

Avacopan is under clinical development by Amgen and currently in Phase III for Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis (ANCA Vasculitis). According to GlobalData, Phase III drugs ...

Objectives A few studies on antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) treatments have shown the therapeutic efficacy of mycophenolate mofetil (MMF). However, the ...

A 79-year-old keen cyclist from Willunga man credits positive thinking with saving him from a rare disease, ANCA vasculitis, after he experienced severe pains while in Thailand. Roger Fabray ...

MT-2990 is under clinical development by Mitsubishi Tanabe Pharma and currently in Phase I for Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis (ANCA Vasculitis). According to GlobalData, ...

AAV is a multisystem disease typified by small vessel inflammation accompanied by a positive serum ANCA. While systemic vasculitis is a characteristic shared across the AAV spectrum, the formation of ...

This search was performed using the PubMed database with keywords such as “ANCA-associated vasculitis,” “polyangiitis,” “granulomatosis ... in which the authors collectively reported on 14 patients ...

see Table 1). Patients with vasculitis are at increased risk of thromboembolic events as pregnancy is a further thrombotic risk factor; aspirin and/or heparin may need to be considered.