Abstract We investigated the effects of angiotensin II (Ang II) type 1 receptor blockade with losartan on the renin-angiotensin-aldosterone system in hypertensive patients (supine diastolic blood ...

Angiotensin II (AT-II)-Receptor Antagonists are Reviewed. Research focused on blocking the renin- angiotensin system (RAS) led to the discovery of angiotensin-converting-enzyme (ACE) inhibitors ...

Abstract We investigated the effects of angiotensin II (Ang II) type 1 receptor blockade with losartan on the renin-angiotensin-aldosterone system in hypertensive patients (supine diastolic blood ...

Numerous clinical studies have established that angiotensin II receptor blockers are effective as antihypertensive therapy and are well tolerated. Studies demonstrate that adding an angiotensin II ...

2004; Bizeau and Pagliassotti, 2005; Farah et al., 2006; Bantle, 2009). Vidotti et al. (2004) described that high glucose levels increase angiotensin II (Ang II) generation in mesangial cells as a ...

while ACE further converts it to angiotensin II — a potent vasoconstrictor among other things — leading to an increase in blood pressure. Two classes of antihypertensives target angiotensin II ...

A recent study suggests that a commonly prescribed type of blood pressure medication, known as angiotensin receptor blockers ...

Paraquat (1,1’-dimethyl-4,4’-bipyridyl dichloride) is a non-selective herbicide still widely used in agricultural crops in vast regions around the world for weed control (Zobiole et al. 2018) and also ...

In line with trial results, real-world data suggest GLP-1 receptor agonists have certain benefits in patients with moderate to severe chronic kidney disease (CKD).

Design Cultured human colonic myofibroblast proliferation and collagen secretion were assessed following treatment with angiotensin (Ang) II and Ang (1–7), their receptor antagonists candesartan and ...