We further show that serum from young autistic patients contains mtDNA (n = 20; cytochrome B, p = 0.0002 and 7S, p = 0.006), and anti-mitochondrial antibody Type 2 (n = 14; p = 0.001) as compared ...

For instance, mtDNA (or other extracellular mitochondrial components not measured in this study) could activate TLRs on immune or glial cells to release pro-inflammatory cytokines, such as IL-6 ...

Anti-CCP antibodies were analysed by an enzyme immunoassay (EIA). Rheumatoid factors (RFs) were analysed by latex agglutination and two isotype-specific (IgM and IgA) EIAs. Disease activity was ...

To fill this knowledge gap, Ikeda and colleagues obtained tumour-infiltrating T cells and cancer cells from human tumours that were surgically removed and sequenced the mitochondrial DNA (mtDNA ...

Anti-malarial monoclonal antibodies (mAbs) are another promising new tool that have been shown to be safe and efficacious against infection with P. falciparum in adults and children in early ...

Sjögren’s antibody testing is done using a blood sample. It checks antibody levels, including anti-SS-A (also called anti-Ro) and anti-SS-B (also called anti-La). Anti-SS-A and anti-SS-B are ...

Scientists have discovered a new type of anti-malarial antibody that doesn't interfere with current vaccines, at least in mouse models. Could they help eliminate malaria in the future? https://p ...

lumc.nl Objective The presence of anti-citrullinated protein antibodies (ACPA) and IgM-rheumatoid factor (IgM-RF) years before the clinical diagnosis of rheumatoid arthritis (RA) suggests they are ...

Anti-malarial monoclonal antibodies (mAbs) are another promising new tool that has been shown to be safe and efficacious against infection with P. falciparum in adults and children in early ...

Various external factors modulate the metabolic efficiency of mitochondria. This review focuses on the impact of the growth factor neuregulin and its ErbB receptors on mitochondria and their ...

To determine whether mitochondrial formylated peptide induced migration was a Mac1-dependent process, neutrophils preincubated with either anti-CD11b antibody or appropriate isotype control were ...