Protective role of Pannexin1 in lymphatic endothelial cells in the progression of atherosclerosis in female mice. Extracted ...

Here, we studied mice deficient in apolipoprotein E (apoE-null)(refs. 16,17); in these mice, severe hypercholesterolemia despite eating a normal chow diet causes atherosclerosis. To determine ...

Objective To investigate the effects of vaccination against AGE-LDL in atherosclerosis and involved mechanism. Results Compared with Al(OH) 3 or PBS alone, combined immunisation could significantly ...

To study the complex interplay between APOE variants and brain cells, Huang and his team have long relied on mouse models, just as many other research groups do. However, mimicking the human brain ...

Analyzing the lipids and related proteins in the bone marrow of anemic mice showed that although VLDL levels decreased, ...

Results: Over a median 5.6 year follow up, Alzheimer’s disease was diagnosed in 206 subjects. Compared with APOE ε3/ε3 genotype, the relative risk (RR) of Alzheimer’s disease was 1.4 (95% confidence ...