Apoptotic cell death is a critical process in natural tissue homeostasis and results in immediate removal of the dying cells. In January Journal of Clinical Investigation Mai-Lan Huynh and colleagues ...

As an example, Atg5 is an essential autophagy inducer, yet it can be cleaved by calpain cysteine proteases to lose its pro-autophagy effects and become a pro-apoptotic molecule. Beclin-1 (or its ...

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Because mutations of this receptor or its ligand lead to autoimmune disorders such as systemic lupus erythematosus (SLE) and cancers, CD95 and CD95L were initially thought to play a role in immune ...

Objective Liver injury impacts hepatic inflammation in part via Toll-like receptor (TLR) signalling. Triggering receptor expressed on myeloid cells 2 (TREM-2) modulates TLR4-mediated inflammation in ...

"This hormone actually tells our bodies to ignore feelings of pain and fatigue while enhancing blood flow to large muscles." A workout can leave you with more energy than you had beforehand ...

Diabetic nephropathy (DN) is the main cause of end-stage renal disease (ESRD), which is characterized by a series of abnormal changes such as glomerulosclerosis, podocyte loss, renal tubular atrophy ...

The inactivation of programmed cell death has profound effects not only on the development but also on the overall integrity of multicellular organisms. Beside developmental abnormalities, it may lead ...

Read more here. Body lotion benefits your legs, knees, arms, butt, and torso in much the same way that a daily moisturizer benefits the skin on your face. According to dermatologist Dr.

The management of Leishmania donova ni (LD), responsible for fatal visceral leishmaniasis (VL), faces increasing challenges due to rising drug-unresponsiveness, leading to increasing treatment ...

15 16 In this work, we combined scanning electron microscopy (SEM), transmission electron microscopy (TEM), atomic force microscopy (AFM) and focused ion beam-SEM (FIB-SEM) with high-resolution ...

The body contains all the internal organs, body parts, bones and muscles that make up the human anatomy. Your fleshy body has evolved over millions of years, and this is the science changing the way ...