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Beclin-1 (or its yeast homologue Atg6) interacts with the anti-apoptotic ... the sense that, under certain circumstances, autophagy constitutes a stress adaptation that avoids cell death (and ...

We recently observed that the soluble ligand is overexpressed in serum from patients with triple-negative breast cancer or SLE, in whom it contributes to disease severity by activating non-apoptotic ...

Cells navigating in complex microenvironments frequently encounter narrow spaces that physically challenge migration.

NRVMs and H9C2 cells were treated with Naringin at a dose of 50 μM in culture medium after cell generation, Doxorubicin hydrochloride was administrated at a dose of 5 μM after Naringin treatment.

Feb. 4, 2025 — Research has shown that a potential new targeted therapy for childhood brain cancer is effective in infiltrating and killing tumor cells in preclinical models tested in mice.

Jan. 23, 2025 — There's a downside to being a powerful alpha male -- at least if you're a baboon. Studies show that despite their high rank, the No. 1 males in baboon society are also some of ...

The management of Leishmania donova ni (LD), responsible for fatal visceral leishmaniasis (VL), faces increasing challenges due to rising drug-unresponsiveness, leading to increasing treatment ...

The inactivation of programmed cell death has profound effects not only on the development but also on the overall integrity of multicellular organisms. Beside developmental abnormalities, it may lead ...

eLife is a non-profit organisation inspired by research funders and led by scientists. Our mission is to help scientists accelerate discovery by operating a platform for research communication that ...