China) were used to monitor nuclear DNA fragmentation in the late apoptotic process of cells. A 4′,6-diamidino-2-phenylindole (DAPI) solution was used to dye nuclei. Finally, the samples were analyzed ...

Apoptotic cells were observed for 2n, 4n or >4n after overnight incubation but significant ... In addition, 15% of the cells were mononuclear with polyploid nuclei, and 24% were binuclear cells with ...

Because mutations of this receptor or its ligand lead to autoimmune disorders such as systemic lupus erythematosus (SLE) and cancers, CD95 and CD95L were initially thought to play a role in immune ...

a Liver Research Group, Division of Cell and Molecular Medicine, Level D, South Lab and Path Block, Southampton General Hospital, Southampton, UK, b Department of Clinical Pharmacology, University of ...

Similar findings were recorded by Avınca et al. 31. Biochemically oxidative stress increased, histochemically neuronal degeneration, vascular dilatation, inflammation and apoptotic nuclei were ...

PDE2 (phosphodiesterase 2) is upregulated in human heart failure. Cardiac PDE2‐transgenic mice are protected against contractile dysfunction and arrhythmias in heart failure but whether an acute ...

Cell stress stimulates pro-apoptotic signalling pathways that activate caspase proteases and cause mitochondrial dysfunction. Apoptotic cells undergo characteristic changes in cell morphology ...

Correspondence to: Dr G J Gores Mayo Clinic College of Medicine, 200 First St SW, Rochester, Minnesota 55905, USA; gores.gregorymayo.edu ...

The high mobility group A (HMGA) family is composed of four proteins, HMGA1a, HMGA1b, HMGA1c and HMGA2, encoded by two distinct genes. HMGA1 proteins are products of the same gene, generated ...

Correspondence to Professor Hongwei Ouyang, 1. Dr. Li Dak Sum & Yip Yio Chin Center for Stem Cells and Regenerative Medicine, and Department of Orthopedic Surgery of the Second Affiliated Hospital, ...

NCERT Class 12 Physics Chapter 13 Nuclei Solutions: With the 2025 board exams approaching fast, it’s time for students to review the syllabus and start practising questions and sample papers.