The results of a phase III trial confirm the place of canakinumab in the treatment arsenal for these disorders. Cryopyrin-associated periodic syndromes (CAPS) are a family of related conditions ...

Primary progressive aphasia (PPA) is a disorder of declining language that is a frequent presentation of neurodegenerative diseases such as frontotemporal lobar degeneration. Three variants of PPA ...

A surprising mix of inherited and de novo mutations in 60 genes contribute to 10 percent of CHD cases. Many of these same ...

Muckle-Wells syndrome is one of several diseases known as cryopyrin-associated periodic syndromes. In these conditions, a mutation (change) in a particular gene causes more activity of the protein ...

New-onset psychosis in HIV-seropositive patients has prevalence estimates ranging from 0.5 to 15%, [91] and is most often seen in neurocognitive disorders, such as delirium, HIV-associated ...

Feb. 17, 2021 — The mutation of a gene that has been associated with neurodevelopmental disorders like autism spectrum disorder led to marked sleep disturbances in fruit flies, according to a ...