A research team revealed that insulin-like growth factor-binding protein 6 (IGFBP6) serves as a potential therapeutic target ...

Protective role of Pannexin1 in lymphatic endothelial cells in the progression of atherosclerosis in female mice. Extracted ...

Atherosclerosis risk is elevated in diabetic patients, but the underlying mechanism such as the involvement of macrophages remains unclear. Here, we investigated the underlying mechanism related to ...

16,17); in these mice, severe hypercholesterolemia despite eating a normal chow diet causes atherosclerosis. To determine whether induction of diabetes would accelerate the incidence and ...

A research team led by Prof. WENG Jianping from the University of Science and Technology of China (USTC) of the Chinese ...

Real-time observation of certain biochemical processes in blood vessels from mice has revealed a previously unknown similarity between atherosclerosis, also known as vascular calcification, and bone ...

Modified HDL has been used extensively in atherosclerotic mice to detect macrophage levels in plaques using MRI and has excellent potential for similar clinical applications. Given the addition of ...

Ley has received research funding for developing an atherosclerosis vaccine formulation from United Bioscience, Inc. The other author reports no conflicts. This work was supported by grants to D. Wolf ...

Mice have been trying to help humans become healthy for over a century. Unfortunately, the humans are not reciprocating. The ...

We appreciated the FDA reviewers' alignment with our proposed clinical development program, and their positive feedback on our intended clinical trial design, IND-enabling studies, and drug ...