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FiercePharma
12 小时
Pfizer's blockbuster ADC Adcetris nabs FDA approval to treat large B-cell lymphoma
More than 13 years after its initial FDA approval, Pfizer’s blood cancer drug Adcetris has nabbed another regulatory green ...
The American Journal of Managed Care
6 天
Refining Remission Assessment in Aggressive B-Cell Lymphomas
Despite research showing the benefits of circulating tumor DNA as an indicator of disease remission in B-cell lymphoma, ...
生物通
8 天
Usp11通过去泛素化DLL1和JAG2维持边缘区B细胞在电离辐射下的存活
米托蒽醌作为 Usp11 的抑制剂,给予野生型小鼠米托蒽醌处理后进行 TBI,结果显示米托蒽醌干预使 Usp11+/+ 小鼠脾脏边缘区变窄,减轻了电离辐射后 MZ B 细胞数量的减少。流式细胞术分析表明,米托蒽醌处理后,Usp11+/+ 小鼠受 TBI 后 MZ B 细胞的总百分比显著高于 PBS 处理组,且血清 IgM 水平变化表明米托蒽醌干预减少了抗体类型的转变。这说明靶向 Usp11 ...
8 天
Fate Therapeutics Has Promising Off-The-Shelf Cell Therapies While Looking Cheap
Fate Therapeutics uses iPSC and gene editing to offer scalable off-the-shelf therapies. Read more to see why I rate FATE ...
3 天
on MSN
New gene modification enhances CAR-T cell effectiveness against cancer
Researchers have identified a method to enhance the effectiveness of a promising cancer treatment. They found that modifying a specific gene improves the ability of immune cells to combat cancer for ...
9 天
Govt Approves Qartemi, A Living Drug For Destroying Cancer Cells
A breakthrough CAR-T cell therapy, Qartemi, has been approved for blood cancer patients in India, offering new hope to those ...
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