You won’t experience the same run a second time, so take advantage of the items at your disposal ... Developer Edmund McMillen’s The Binding of Isaac reinvigorated the roguelike genre when ...

Ubiquitin-binding domains (UBDs) are modular elements that bind non-covalently to the protein modifier ubiquitin. Specific ubiquitin–UBD interactions are crucial for the regulation of multiple ...

The Bible offers powerful stories that have influenced faith and morals for centuries. Some, however, pose tough ethical ...

ORLANDO, Fla. – Jonathan Isaac, by his own admission, has spent much of this season searching for solutions. But when the shorthanded Orlando Magic needed him most Sunday, Isaac wasn't just ...

There are also some returning items from last year for those who want to dress up their characters for Valentine's Day later this month. It is also the two year anniversary for the Trading Post as ...

PHOENIX — Facing a deep financial crisis, the Isaac Elementary School District is being placed into state receivership. The Arizona State Board of Education voted Tuesday for the intervention ...

Appeared as the Headless Horseman (walking) in a Bud Light TV commercial (entitled "The Headless Horseman").

Keep in mind that Bungie can change these items at any time. There’s no mention of the broken Ace of Spades as an ornament yet. Screenshot by Dot Esports Episode Revenant is following up on the ...

Billy Basso, the sole developer of Animal Well, has explained that every item in the game has a dual ... RPG with roguelike elements, The Binding of Isaac Rebirth is the sequel to the first ...