Jacobson followed this abnormal RAS in the lung fluid samples to the kinin cascade, an inflammatory pathway that is tightly regulated by the RAS. He found that the kinin system—in which a key peptide, ...

Khan and Alkon, therefore, investigated Erk1 and Erk2 phosphorylation in fibroblast cell lines from patients with AD in response to bradykinin, an activator of PKC pathways. They found that ...

Luke's Medical Center, Chicago, IL 2 Pathways for formation and degradation of bradykinin ACE=angiotensin-converting enzyme; LK=low molecular weight kininogen; HK=high molecular weight kininogen ...