Lidocaine: Lidocaine has a shorter onset of action than bupivacaine, so it starts to work faster, on average, in less than two minutes, when injected into a vein (intravenously).

Intradermal testing with lidocaine 1%, mepivacaine 2%, and bupivacaine 0.5% was performed on 8 patients; 3 had positive reactions to lidocaine, and 1 had a positive reaction to mepivacaine.

Intradermal test results with lidocaine 1%, mepivacaine 2%, and bupivacaine 0.5% were positive for lidocaine and mepivacaine. The positive lidocaine intradermal test reaction was not vesicobullous ...