In contrast, after adding 20 mg/kg of monoclonal antibody against CD40 ligand to the regimen on days 0 and 2, we observed four thromboembolic complications in nine recipients. These included two ...

研究人员发现 Ellithy 等人研究中 CD40 rs1883832 基因分型错误，影响 ITP 研究结果，需重新审视。 免疫性血小板减少性紫癜（Immune Thrombocytopenic Purpura，ITP）是一种常见的获得性自身免疫性出血性疾病，患者体内血小板被免疫系统错误攻击，导致血小板计数降低 ...

LUND, SWEDEN / ACCESS Newswire / March 21, 2025 /Alligator Bioscience (Nasdaq Stockholm:ATORX) today announces that Dr. Sumeet Ambarkhane MD, Chief Medical Officer, will be leaving Alligator by end of ...

CD40 agonistic antibodies mimic the natural interaction between the CD40 receptor and its ligand, CD40L, triggering immune responses through cytokine release and T-cell activation. This approach ...

Frexalimab is described by Sanofi as a ‘second-generation’ anti-CD40L antibody that can block the costimulatory CD40/CD40L cellular pathway necessary for adaptive and immune cell activation ...

This post was written and published as a collaboration between the in-house editorial team at Benzinga and Tonix ...

EnnoDC presents positive Phase I data at CROI 2025, demonstrating long-lasting immunity induced by Antibody Mediated Vaccines (AMVs)Findings in ...

Abiprubart, an antibody that inhibits the signaling between CD40 and CD154, was in development in a competitive niche but Kiniksa had previously presented that as a positive. Last month ...

In fact, the B cells can actually switch gears, producing antibodies that are different ... It's a process that relies heavily on the interaction of CD40 and CD40L. Using techniques like ...