在药物联用引发的药物相互作用问题日益凸显的背景下，研究人员开展了针对细胞色素 P450（CYP）3A4 选择性抑制剂的研究。他们通过高通量筛选等手段，发现了一系列选择性 CYP3A4 抑制剂，并揭示了其选择性抑制的机制，为设计更优的抑制剂提供了指导。

Ubrelvy can interact with medications that are CYP3A4 inducers. Interaction result: Taking Ubrelvy with a CYP3A4 inducer may make Ubrelvy less effective at treating your condition. Interaction ...

This information is generalized and not intended as specific medical advice. Consult your healthcare professional before taking or discontinuing any drug or commencing any course of treatment ...

This information is generalized and not intended as specific medical advice. Consult your healthcare professional before taking or discontinuing any drug or commencing any course of treatment ...

Naldemedine was safe and effective and reduced health care resource utilization among adults with opioid-induced constipation and chronic noncancer pain.

Concomitant use or discontinuation of CYP2B6/CYP3A4 inhibitors or inducers: monitor closely and consider dose adjustments (see full labeling). For elderly: use lower end of dosing range.

Dexamethasone phosphate (as sodium); 4mg/mL, 10mg/mL; soln for IV or IM inj; contains sulfites. Potentiated by CYP3A4 inhibitors (eg, ketoconazole, macrolides), cyclosporine, estrogens ...