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Summary. Doripenem, a member of the β-lactam class of antibiotics, is the newest addition to the carbapenems. It exhibits concentration-independent bactericidal activity against gram-positive ...

The carbapenem antibiotics (imipenem, meropenem and doripenem) are considered the agents of choice for A. baumannii infections. The presence of resistance to these agents constrains therapeutic ...

Wockhardt Limited announced that its innovative antibiotic, Zaynich (Zidebactam/Cefepime), demonstrated over 97% clinical efficacy in treating serious infections ...

Carbapenem-resistant Enterobacteriaceae (CRE ... Disruption of the microbiome, caused by factors such as antibiotic use, diet, and disease, can create ecological niches that favor the colonization of ...

Sepsis caused one in five deaths globally in 2020, according to the WHO. Essentially, the world sees 11 million deaths due to ...

In Latin America, it appears that bacteria resistant to carbapenem antibiotics have different resistance mechanisms than similar bacteria found in Africa and Asia. Two pathogens are of particular ...

That includes improving local data about co-morbidities that can affect the ability of antibiotics to work. Among the most important AMR targets are carbapenem-resistant bacteria. In Latin America ...

In a new study published in the journal The Lancet, researchers have explored the possibility of treating acute, non-perforated appendicitis in children with antibiotics instead of surgery.

Tebipenem is the first oral drug in the carbapenem antibiotic class to reach late-stage development and, despite the desperate need for new antimicrobials, was turned down in June by the FDA ...