Innovative microfluidic platforms facilitate the study of cardiomyocyte function, offering valuable data for drug testing and ...

Innovative muscle patches derived from stem cells demonstrate efficacy in heart repair, improving function in primates and a ...

High doses of WNT signaling promote cavity expansion and cardiomyocyte specification. HAND1 ... Functional properties were assessed using video-based analysis and microelectrode arrays (MEAs) for ...

This fundamental work extends our understanding of the role of TGFβ2 as a modulator of mechanosensing in the eye and identifies the TRPV4 ion channel as a common regulator of Trabecular Meshwork (TM) ...

All methods to measure membrane potential, calcium flux or the contractility can be placed under the heading “measurements of the cardiomyocyte contraction cycle”. These measurements must be carried ...

Protein kinase C, in particular PKCα, also worsens calcium cycling and contractility. New bisindolylmaleimide inhibitors of PKC (Ro-32-0432, and Ro-31-8220) improve function. Last, nuclear ...

interstitial fibrosis and reduction in contractility and relaxation (Remme 2003). The use of MPTP did not change the CMF or the CI total volumes, but the toxic effect of MPTP decreased the total ...

This review examines the giant elastic protein titin and its critical roles in heart function, both in health and disease, as discovered since its identification nearly 50 years ago. Encoded by the ...