Natural killer (NK) cells are effector cells of the innate immune system that play a key role in the control of intracellular pathogens and tumours, especially against those that evade adaptive ...

The LNP-mRNA modality is a novel approach that uses lipid nanoparticles to deliver messenger RNA into cells. The mRNA acts as ...

A phase 1 study of a personalized cancer vaccine demonstrated antitumor immunity in all treated patients with resected renal ...

Adaptive immunity is the protection of a host organism from a pathogen or toxin. It is mediated by B cells and T cells, and is characterized by immunological memory. Adaptive immunity is highly ...

Immunizing the host with a piece of viral DNA rather than an antigenic protein fragment of the virus, helps to stimulate the generation of cell-mediated immunity (Fig. 2). DNA vaccines contain the ...

Cells navigating in complex microenvironments frequently encounter narrow spaces that physically challenge migration.

The three-signal model provides an empirical framework for innate instruction of adaptive immunity, but mainly discusses STAT-dependent cytokines in T cell activation and differentiation, while the ...

Induces potent and long-lasting immune responses to defined antigens or whole pathogens (particles), mainly through the ...

Looking forward, it might also be possible to use T-cell testing for this purpose ... If so, it is discriminatory to treat natural immunity differently to vaccine-mediated immunity, and this is ...

Scientists from DZNE, University Hospital Bonn (UKB) and the University of Bonn provide new evidence that preventing brain ...

In contrast, oversized cells that undergo compensatory growth slowdown exhibit a superlinear increase in proteasome-mediated protein degradation, with accelerated protein turnover per unit mass, ...