本文聚焦 cGAS-STING 通路重编程肿瘤相关巨噬细胞（TAMs），探索其增强抗肿瘤免疫治疗的潜力。 ### 一、抗肿瘤免疫治疗面临的挑战与机遇 在全球范围内，抗肿瘤治疗始终是一项极具挑战性的任务。当前，手术、放疗、化疗、免疫治疗等多种手段被广泛探索应用于 ...

Researchers from Soochow University and affiliated organizations presented data from a study that aimed to investigate the role of cyclic GMP-AMP synthase (cGAS) in tumorigenesis and tumor progression ...

Researchers atBellBrookLabs have developed a high throughput screening (HTS) compatible biochemical assay to discover and advance small molecule modulators for the target cyclic GMP-AMP synthase (cGAS ...

A key part of this discovery, made by a team from the Swiss Federal Institute of Technology Lausanne, is an enzyme called cyclic GMP-AMP synthase (cGAS). This protein is tasked with identifying ...

Because cGAS was the only candidate that produced cGAMP activity ... In this webinar, Daryl Cole will share insights into the high-throughput screening and analysis of antibody binding and functional ...