Here we could show that tumor cells of PC besides being senescent also exhibit stem cell features. To investigate these surprising findings in more detail, we established a murine model based on tumor ...

To create one of the most advanced immunotherapies in cancer, CAR-T cell therapies, scientists engineer immune T cells to carry a synthetic protein on their surfaces. This protein, called the ...

Get Instant Summarized Text (Gist) Research has uncovered why tumor cells die differently after radiotherapy, revealing that DNA repair pathways dictate the mode of cell death. When homologous ...

Investigators examined how molecular dynamics at the immune synapse -- where CAR T cells bind to cancer cells -- affect anticancer activity. A study published in Science Advances shares new ...

Brain Tumor Organoids Accurately Model Patient Response to CAR T Cell Therapy Dec. 9, 2024 — Researchers used lab-grown organoids created from tumors of individuals with glioblastoma (GBM ...

Non-small cell lung cancer (NSCLC) is the most common form of lung cancer, accounting for 80 to 85% of all cases of lung cancer. There are different stages of NSCLC, ranging from 0 to 4; ...

Houston Methodist Hospital and Texas Children's Hospital examined how molecular dynamics at the immune synapse—where CAR T cells bind to cancer cells—affect anticancer activity. In this study ...

What about inflammation? And how do tumors spread? Here’s what scientists are learning about this complex disease. By Nina Agrawal Every day, billions of cells in our body divide or die off.

Glioblastoma multiforme (GBM) is the most common aggressive primary brain cancer. Brain cancers are classified into either glioma (i.e., tumors originating from glial cells) or non-glioma. Based on ...

In lab-dish experiments, the sEVs specifically move towards and bind to DR5 and quickly killed cancer cell types that have high levels of DR5 expression, including melanoma, liver and ovarian ...