In mouse models of PD-L1–positive hematologic and solid tumors, the scFv-secreting CAR-T cells demonstrated enhanced antitumor efficacy compared with conventional CAR-T cells. In addition, a follow-up ...

Siteman Cancer Center at Washington University. But too much estrogen over a lifetime can lead to the formation and growth of cancerous cells. Over time, there have been several population-level ...

In lab-dish experiments, the sEVs specifically move towards and bind to DR5 and quickly killed cancer cell types that have high levels of DR5 expression, including melanoma, liver and ovarian ...

The experts have uncovered why cancer cells respond differently to radiotherapy, with some cells dying in ways that alert the immune system and others dying silently. This difference is linked to how ...

They guide the immune system to find and eliminate cancer cells by binding tumor targets and the CD3 protein on cancer-killing T cells at the same time. However, the development of T-cell engagers ...

They guide the immune system to find and eliminate cancer cells by binding tumor targets and the CD3 protein on cancer-killing T cells at the same time. However, the development of T-cell engagers has ...

Get Instant Summarized Text (Gist) Research has uncovered why tumor cells die differently after radiotherapy, revealing that DNA repair pathways dictate the mode of cell death. When homologous ...