Monosomy X accounted for < 10% of all abnormalities ... Because advanced maternal age is associated with an increased risk of fetal chromosome abnormalities, the ages of the women in the two ...

Chromosome abnormality is the condition in a cell or organism where the number of chromosomes or the structure of any chromosome differs from the normal karyotype. When the variant genotype is not ...

39 We hypothesise that in the OFDI syndrome, as for the other X-linked dominant disorders, X inactivation may affect the phenotype of heterozygous females. Thauvin-Robinet et al analysed X chromosome ...

The X and Y chromosomes ... Created with Sketch. This rare sex chromosome abnormality, also referred to as Jacob’s syndrome, occurs when a male infant is born with an extra Y chromosome.

2013;13(6):601-611. In other situations, normal microarray analysis in the presence of an abnormal karyotype, such as marker chromosomes, is reassuring, as it indicates that the marker is lacking ...

A new study reveals that the maternal X chromosome may accelerate brain ageing and increase Alzheimer's risk. Experiments on female lab mice showed th ...

A study conducted by a research team at the Crick Institute identified important genes on the Y chromosome that regulate ...

Women are born with two X chromosomes and inherit one from each parent. But in every cell of their body, just one X chromosome is needed—so the other is randomly inactivated. Some cells use only ...

Extra X chromosomes significantly increase the risk for systemic lupus erythematosus (SLE) and Sjögren disease, with the prevalence of these conditions being higher among patients with ...

Lee and her colleagues have theorized that in cases where genetic disorders are the result of a mutation on the X chromosome, the inactivated X chromosome could serve as a "backup copy," and that ...

Women have longer lifespans but are at a higher risk of developing some brain disorders. Role of X chromosomes in brain function and ageing Humans have two sex chromosomes—females carry two X ...

Female mammals typically carry two X chromosomes — one from each parent — and a new study suggests that the maternal X is linked to faster brain aging. The X chromosome passed from mom to ...