For a living cell to divide successfully, each daughter cell must inherit the correct genetic material. In eukaryotes, segregation of duplicated chromosomes is performed by the mitotic spindle, a ...

For this, the cell must duplicate its DNA – its genome – and segregate it equally into two new daughter cells. To prepare the 46 chromosomes of a human cell for transport to the daughter cells during ...

A new study has shown how chromosomes change shape during cell division. Certain protein complexes help fold DNA into overlapping loops that repel each other, which then stack to create a rod-like ...

As the cell proceeds through the stages of cell division (from left to right: interphase, prometaphase, metaphase, and anaphase), chromosomes become progressively more compact through a ...

To prepare the 46 chromosomes of a human cell for transport to the daughter cells during cell division, each chromosome forms a compact X-shaped structure with two rod-like copies. How the cell ...

The five phases of mitosis and cell division tightly coordinate the movements of hundreds of proteins. How did early biologists unravel this complex dance of chromosomes? The most obvious ...

Scientists at EMBL have captured how human chromosomes fold into their signature rod shape during cell division, using a ...

The biological research of UC Santa Cruz’s Needhi Bhalla to determine the molecular motions at the heart of heredity has ...

Each human body cell contains 46 chromosomes. These can be arranged into 23 pairs. Each chromosome in a pair carries the same types of genes. The 23rd pair are the sex chromosomes: In females ...

For generations, a tiny piece of DNA has mastered the art of inheritance by hijacking the yeast cell’s division machinery, ...

The improper segregation of chromosomes during cell division leads to abnormalities that disrupt the proper functioning of the cell. Cells with an abnormal number of chromosomes consequently activate ...

A decade earlier, my doctoral work had centered on trying to understand how chromosomes in normal cells are evenly distributed between the two daughter cells during mitosis. The process is so ...