Adrenal insufficiency or bilateral oophorectomy (surgical menopause) result in severe androgen deficiency, which can be clinically associated with impaired libido, drive and energy. Physiological ...

Medically reviewed by Lauren Schlanger, MD Androgen insensitivity is an umbrella term for a number of genetic conditions where the body does not respond appropriately to testosterone and other ...

This approach goes by several names: combined androgen blockade, complete androgen blockade, or total androgen blockade. Here's a rundown of the techniques. Luteinizing hormone-releasing hormone ...

We have discovered two types of 5′ intronic gene mutation that impair androgen receptor (AR) mRNA expression severely, and cause complete androgen insensitivity. Labium majus skin fibroblasts ...

GU ASCO annual meeting featured a prostate cancer session and a presentation by Dr. Miguel Muniz discussing outcomes for 177 Lu-PSMA-617 with and without concurrent use of androgen receptor pathway ...

Hormonal therapy, namely targeting androgen signaling, has continued to be the mainstay of treatment for advanced prostate cancer, going all the way back to the 1940s when we first started using ...

To do this, they developed the "Androgen Clock," an analysis platform which examines specific DNA regions that change over time in the presence of androgens. While researchers have not yet been ...

We briefly review initial studies of the preoperative use of agents targeting androgen metabolism, with results not uncommonly showing complete or near-complete pathologic response. Finally ...