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《癌细胞》:更新换代,效果不赖!临床前研究显示,新一代CDK4选择 ...
从研究结果上看,Atirmociclib作为一种CDK4选择性抑制剂,与现有的CDK4/6抑制剂哌柏西利相比,其在结构上对CDK4的亲和力更高,选择性更强,能在增加对CDK4靶点覆盖率,提升疗效的同时,降低对CDK6的抑制,减少对中性粒细胞的影响。
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