Blood TCTP as a biomarker associated with immunosuppressive features and resistance to immunotherapy in metastatic gastric cancer. This is an ASCO Meeting Abstract from the 2025 ASCO Gastrointestinal ...

Tyrosine (Tyr) phosphorylation of p27 by Abl and Src family kinases reduces p27–CDK2 inhibition and transforms p27 from inhibitor to substrate of cyclin–CDK2 complexes. p27 phosphorylation at ...

MAMMOTH and DENALI studies and shared details on future clinical development and potential registration plans for patients with Cyclin E1+ platinum-resistant ovarian cancer (PROC). Results from ...

Cancer remains the second leading cause of death in the US, accounting for 25% of all deaths nationwide. Immunotherapy techniques bolster the immune cells’ ability to target malignant cancer cells and ...

The main contributions of this study are as follows: (1) We build a large Multiplex IHC Histopathological Image Classification (MIHIC) dataset for lung cancer TIME quantification, which consists of 12 ...

Effect of tRF-28-ZJ47D112Z4DZ on the pathogenesis of gastric cancer through targeting cyclin D1/CDK4 and its early diagnostic value. This is an ASCO Meeting Abstract from the 2025 ASCO ...

According to research, PSAT1, PSRC1, COLEC12, HP, and PLLP may play a role in small cell lung cancer metabolism, immune ...

Results from the combination cohorts of MAMMOTH and from the ZN-c3-016 study in colorectal cancer were also disclosed today. “We are excited to outline a clear path for Zentalis to bring azenosertib ...

Jan. 15, 2025 — In patients with high-risk HER2-positive breast cancer, post-surgery, or adjuvant, treatment with trastuzumab emtansine (T-DM1) reduced the long-term risk of death or invasive ...

The American Cancer Society's latest cancer report shows both positive and concerning trends: overall cancer deaths are down but the number of women and young adults with cancer is up. The annual ...

Although common, the cause of these hernias is unknown, and the only treatment ... Cancer Vaccine Shows Promise for Patients With Stage III and IV Kidney Cancer Feb. 5, 2025 — Researchers report ...