LIG4 syndrome is an exceptionally rare disorder caused by a genetic mutation that prevents the body from repairing damaged DNA.

In addition, the increasing demand for ligases in applications and DNA modifying enzymes is a contributory factor. What does the next decade hold for the DNA Modifying Enzymes Global Market?

UBE3A is an E3 ubiquitin ligase encoded by an imprinted gene whose maternal deletion or duplication leads ... effects of different UBE3A expression levels in human neuronal cell culture models ...

Lac directly binds the E3 ligase STUB1, leading to increased polyubiquitination and proteasomal degradation of RUNX1. Lac inhibits Tregs activity and promotes antitumor immunity in a mouse primary ...

R&D revenues for fourth quarter 2024 were $11.6 million compared to $8.5 million in fourth quarter 2023. The increase was primarily due to Pfizer applying the last portion of the retainer fee toward ...

In summary, poxviruses encode PRANC proteins that can bind SKP1. The cullin-based E3 ubiquitin ligase consists of three functional components: a catalytic component consisting of a small RING domain ...

Learning about your genetics and ancestry is easier than ever. All you need to do is choose from the many DNA ancestry tests available online, receive your kit and send back the required DNA samples.