In a study published in Nature, researchers report the successful in vitro reconstitution of meiotic DNA double-strand breaks ...

The tethered DNA strand was comprised of a double-stranded (dsDNA ... However, DNA polymerase’s activity appeared seamless and uniform, so the team considered that a process existed to help one enzyme ...

Different cells have different activities. By controlling protein synthesis within each cell, the genes that make up DNA control the ... can be working on a single strand of mRNA at once.

When a cell divides, it makes a copy of its DNA instructions for the new cell. The twisted double strand structure -- the famed double helix -- unwinds and the strands separate. The nucleotides (A ...

Researchers have revealed new details about the CRISPR-Cas5-HNH/Cascade complex, a variant of the type I-E CRISPR-Cas system, ...

Once access has been gained, Rad51 polymerizes on the DNA strand to form what is called ... In addition to proteins that assist Rad51 activity, there are also some proteins that inhibit it.

Roche has put forward a new approach to genetic analysis, which it describes as sequencing-by-expansion—a proprietary method ...

In eukaryotes, DNA is tightly wound into a complex called chromatin. Thanks to the process of chromatin remodeling, this complex can be "opened" so that specific genes are expressed. Various ...

The DNA repair and replication pathways converge on a common final step in which the continuity of the repaired DNA strand is restored by DNA ligase, an enzyme that converts nicks into phosphodiester ...

Normal metabolic activity produces reactive oxygen species (ROS ... While nuclear DAAO activation kick-started DNA damage repair proteins and caused DNA strand breaks, mitochondrial-bound DAAO did not ...

RNA polymerase moves along the DNA strand. Free RNA nucleotides form hydrogen bonds with the exposed DNA strand nucleotides by complementary base pairing to form a strand of mRNA: Note - RNA ...